Hydrochloric Acid → HCID 18329725, compound

Participants

Reaction Steps

Concentrated hydrochloric acid (1 ml) was added to a stirred solution of (−)-6,7-dichloro-5-[3-methoxymethyl-5-(1-oxidopyridin-3-yl)-4H-1,2,4-triazol-4-yl]-2,3(1H,4H)-quinoxalinedione, silica complex (See Reference Example 1) (2.3 g, 4.64 mmol) in methanol (40 ml) and the mixture stirred for 2 hours. The solid precipitate was collected by filtration to afford the title compound as a white solid (1.4 g, 65%). mp 264-265° C.

Provenance & Evidence