1,3-Benzodioxol-5-amine → HCID 178500748, compound

Participants

Reaction Steps

Experimental conditions analogous to those described for Step 1 of Example 1, from crude 2-(3,4-dimethyl-benzoyl)-3-methoxy-acrylic acid methyl ester (4.03 g, 16.3 mmol) and benzo[1,3]dioxol-5-ylamine (2.45 g, 17.9 mmol). Yield: 3.14 g of a yellow crystalline solid: LC-MSD, m/z for C20H20NO5 [M+H]+=354.4; HPLC retention time: 2.8 min.

Provenance & Evidence