Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | HCID 12652148 | HCID 12652148 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 11347883 | HCID 11347883 | — |
Reaction Steps
A solution of 2-hydroxy-3,5,di-t-butylbenzylamine (prepared by the procedure described by G. E. Stokker, et al.; J. Med. Chem. 1980, 23, 1414; 2.35 g, 10.0 mmol) is prepared in 50 mL methanol. Benzaldehyde (1.06 g, 10.0 mmol) is added, and the resulting solution is stirred for 30 minutes. Product crystallizes upon cooling the solution to −40° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06333389B1 |
|---|
| Source dataset | uspto-grants-2001_12 |
|---|
| ORD ID | ord-b1558e714da24b0182cb0ac7fa0ed0b4 |
|---|
| Source note | uspto-grants-2001_12 |
|---|
