DL-Benzoin benzoate → Benzilam

HRID 2271229Notes

Reaction equation

HRID 2271229 reaction equation
[C:1]([O:9][CH:10]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[C:11](=O)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:25]C(N)=S>CN(C)C=O>[C:2]1([C:1]2[O:9][C:10]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[C:11]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[N:25]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 246708DL-Benzoin benzoateHCID 2723790Thiourea

Product 1

HCID 275930Benzilam

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
160 °C

Procedure

1 g of desyl benzoate and 0.5 g of thiourea (2 eq.) are added to 10 ml of dimethylformamide in a reactor. The solution is left stirring at 160° C. for 7 hours.

Workup

  1. waitThe solution is left

Sources & evidence

ORD record
ord-77e839ea24d041508033e98cc2c8f3c5
Source dataset
uspto-grants-2001_12
Patent number
US06333414B1

Reaction notes

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