Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 70676150 | HCID 70676150 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 70676330 | HCID 70676330 | 97% |
Reaction Steps
1N HCl (3 mL) was added to 10 mL of tertiary butyl 3-((3,4-dichlorophenyl)(phenoxy)methyl)azetidine-1-carboxylate (150 mg, 0.352 mmol) dissolved in a methanol solution, and heated to reflux at 60° C. for one day. Thereafter, the solvent of the reaction mixture was removed by reduced pressure evaporation to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09120771B2 |
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| Source dataset | uspto-grants-2015_09 |
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| ORD ID | ord-93bc20a08d9041a0b7ad8d0f4530eab1 |
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| Source note | uspto-grants-2015_09 |
|---|