Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | HCID 86722612 | HCID 86722612 | — |
| Product | HCID 86722613 | HCID 86722613 | 97% |
Reaction Steps
1 N HCl (3.0 mL) was added to 10 mL of tertiary butyl 3-(1-(3,4-dichlorophenyl)-2-(methylsulfonyl)ethyl)azetidine-1-carboxylate (0.15 g, 0.36 mmol) dissolved in the methanol solution and heated to reflux at 60° C. for one day. Thereafter, the solvent of the reaction mixture was removed by reduced pressure evaporation to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09120771B2 |
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| Source dataset | uspto-grants-2015_09 |
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| ORD ID | ord-b84ee1e4de4942dd8cd64db1e509e761 |
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| Source note | uspto-grants-2015_09 |
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