反应详情

To a solution of tert-butyl methyl(1-(5-nitropyridin-2-yl)piperidin-3-yl)carbamate (1.03 g, 3.1 mmol) in THF (50 mL) was added Pd/C (10 wt. %, 500 mg). The reaction mixture was stirred under 1 atm of hydrogen for 16 h, filtered through celite and concentrated to afford the desired product (902 mg, 96%) as a red oil. ESI MS m/z 307 [C16H26N4O2+H]+

1. filtrationfiltered through celite
2. concentrationconcentrated