HRID2271543

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID66715483

1-(6-Bromo-4-chloroquinolin-3-yl)ethan-1-one

C11H7BrClNO

结构：CN(C(=O)OC(C)(C)C)C1CCCN(c2ccc(N)cn2)C1

HCID86692851

未命名化合物

PRODUCTS

生成物

结构：CC(=O)c1cnc2ccc(Br)cc2c1Nc1ccc(N2CCCC(N(C)C(=O)OC(C)(C)C)C2)nc1

HCID86692852

未命名化合物

收率 80.4%

PROCEDURE

实验过程

Following general procedure C, 1-(6-bromo-4-chloroquinolin-3-yl)ethanone (285 mg, 1.0 mmol) was reacted with tert-butyl (1-(5-aminopyridin-2-yl)piperidin-3-yl)(methyl)carbamate (442 mg, 1.45 mmol) to afford the desired product (446 mg, 80%) as an orange-red solid. ESI MS m/z 554 [C27H32BrN5O3+H]+