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HRID2271592

反应详情

EQUATION

反应方程式

HRID 2271592 的结构方程式

REACTANTS

反应物

2
结构：CC(=O)c1cnc2ccc(Br)cc2c1Cl
HCID66715483

1-(6-Bromo-4-chloroquinolin-3-yl)ethan-1-one

C11H7BrClNO

结构：CC(C)(C)OC(=O)N[C@H]1CC[C@H](N)CC1
HCID178419079

未命名化合物

PRODUCTS

生成物

1
结构：CC(=O)c1cnc2ccc(Br)cc2c1N[C@H]1CC[C@H](NC(=O)OC(C)(C)C)CC1
HCID178467071

未命名化合物

收率 80.4%

PROCEDURE

实验过程

Following general procedure B, 1-(6-bromo-4-chloroquinolin-3-yl)ethanone (420 mg, 1.48 mmol) was reacted with tert-butyl trans-4-aminocyclohexylcarbamate (642 mg, 3.00 mmol) to afford the desired product (550 mg, 80%) as an off-white solid: ESI MS m/z 462 [C22H28BrN3O3+H]+.