Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2271601Generated: November 1, 2026

6-(4-Methylpiperazin-1-yl)pyridin-3-amine → HCID 86692873, compound

https://huagongshe.com/reaction/2271601

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(4-Methylpiperazin-1-yl)pyridin-3-amineHCID 2763390—
Reactant1-(6-Bromo-4-chloroquinolin-3-YL)ethanoneHCID 66715483—
ProductHCID 86692873HCID 8669287329%

Reaction Steps

Following general procedure B, 1-(6-bromo-4-chloroquinolin-3-yl)ethanone (200 mg, 0.704 mmol) was reacted with 6-(4-methylpiperazin-1-yl)pyridin-3-amine (163 mg, 0.845 mmol) to afford the desired product (90 mg, 29%) as a yellow solid: ESI MS m/z 440, [C21H22BrN5O+H]+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09120749B2
Source datasetuspto-grants-2015_09
ORD IDord-5381185e852d46b0b29d4db77b8047ea
Source noteuspto-grants-2015_09