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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2271657Generated: November 2, 2026

4-((4-Methylpiperazin-1-yl)methyl)aniline → HCID 68091904, compound

https://huagongshe.com/reaction/2271657

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-((4-Methylpiperazin-1-yl)methyl)anilineHCID 3153996—
Reactant(6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanoneHCID 66715111—
ProductHCID 68091904HCID 6809190456%

Reaction Steps

Following general procedure C, (6-bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone (200 mg, 0.644 mmol) was reacted with 4-[(4-methylpiperazin-1-yl)methyl]aniline (200 mg, 0.966 mmol) to afford the desired product (173 mg, 56%) as a yellow solid: ESI MS m/z 479 [C25H27BrN4O+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09120749B2
Source datasetuspto-grants-2015_09
ORD IDord-bb22de33ea4149a5a40356694b1a5e31
Source noteuspto-grants-2015_09