2-Indanone → Azafluorene

HRID 2272002Notes

Reaction equation

HRID 2272002 reaction equation
[CH2:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][C:2]1=O.[CH2:11]([NH2:14])[C:12]#[CH:13]>>[N:14]1[CH:11]=[CH:12][CH:13]=[C:1]2[C:9]3[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=3[CH2:3][C:2]=12

Participants

3

Reactant 2

HCID 119832-IndanoneHCID 239041Propargylamine

Product 1

HCID 12226515AzafluoreneYield 56%

Procedure

The title compound is prepared from 2-indanone and propargylamine following a procedure analogous to that described in Step 1 of Intermediates 1 and 2. Yield: 56% of theory; Mass spectrum (ESI+): m/z=168 [M+H]+.

Sources & evidence

ORD record
ord-70a8355a54ad44939c6c07cc9b531770
Source dataset
uspto-grants-2015_09
Patent number
US09120769B2

Reaction notes

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