Potassium Hydroxide → HCID 66754919, compound

HRID 227220Notes

Reaction equation

HRID 227220 reaction equation
C[O:2][C:3]([CH2:5][N:6]1[C:15](=[O:16])[C:14]2[N:13]([CH2:17][C:18]#[C:19][CH3:20])[C:12]([N:21]3[CH2:26][CH2:25][CH2:24][CH:23]([NH:27][C:28]([O:30][C:31]([CH3:34])([CH3:33])[CH3:32])=[O:29])[CH2:22]3)=[N:11][C:10]=2[N:9]([CH3:35])[C:7]1=[O:8])=[O:4].[OH-].[K+]>O1CCCC1.CO>[C:3]([CH2:5][N:6]1[C:15](=[O:16])[C:14]2[N:13]([CH2:17][C:18]#[C:19][CH3:20])[C:12]([N:21]3[CH2:26][CH2:25][CH2:24][CH:23]([NH:27][C:28]([O:30][C:31]([CH3:34])([CH3:33])[CH3:32])=[O:29])[CH2:22]3)=[N:11][C:10]=2[N:9]([CH3:35])[C:7]1=[O:8])([OH:4])=[O:2]

Participants

5

Reactant 2

HCID 14797Potassium HydroxideHCID 66753600HCID 66753600, compound

Product 1

HCID 66754919HCID 66754919, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8028TetrahydrofuranSolvent

Procedure

Prepared by saponifying 1-methoxycarbonylmethyl-3-methyl-7-(2-butyn-1-yl)-8-[3-(tert.-butyloxycarbonylamino)-piperidin-1-yl]-xanthine with 4 N potassium hydroxide solution in a mixture of tetrahydrofuran and methanol (5:1) at ambient temperature.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-a11164c39bfb450fbc0f6f1ae6b61360
Source dataset
uspto-grants-2009_07
Patent number
US07560450B2

Reaction notes

Loading…