3-(3,4-dichlorophenyl)-N-methoxy-N-methylpropanamide → 4-(3,4-Dichlorophenyl)butan-2-one

Participants

Reaction Conditions

Reaction Steps

At 0° C. to a solution of 3-(3,4-dichlorophenyl)-N-methoxy-N-methylpropanamide (569 mg, 2.17 mmol) in ether (10 mL) was added drop wise methyl magnesium bromide (2.17 mL, 6.51 mmol) and the solution was stirred at 0° C. for 1 h. The reaction mixture was allowed to warm up to rt and stirred for 18 h.

Provenance & Evidence