2-(4-Bromophenyl)propan-2-ol → 2-{4-[8-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyrazin-2-ylamino]-phenyl}-propan-2-ol

Participants

Role	Name	HCID	Charge
Reactant	2-(4-Bromophenyl)propan-2-ol	HCID 12681920	—
Reactant	8-(1-Methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyrazin-2-ylamine	HCID 66583323	—
Product	2-{4-[8-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyrazin-2-ylamino]-phenyl}-propan-2-ol	HCID 71721801	—

Reaction Steps

2-(4-Bromophenyl)propan-2-ol and 8-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyrazin-2-amine are reacted under Buchwald Hartwig conditions as described in general procedure 2.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09120804B2
Source dataset	uspto-grants-2015_09
ORD ID	ord-f8666d841ebd40c8b1bdfb80f3284ca0
Source note	uspto-grants-2015_09