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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2273008Generated: October 30, 2026

1-(p-Chlorophenyl)cyclopropanecarbonitrile → 1-{4-[8-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyrazin-2-ylamino]-phenyl}-cyclopropanecarbonitrile

https://huagongshe.com/reaction/2273008

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(p-Chlorophenyl)cyclopropanecarbonitrileHCID 98666—
Reactant8-(1-Methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyrazin-2-ylamineHCID 66583323—
Product1-{4-[8-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyrazin-2-ylamino]-phenyl}-cyclopropanecarbonitrileHCID 89767117—

Reaction Steps

Reaction of 8-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyrazin-2-amine with 1-(4-chlorophenyl)-1-cyclopropanecarbonitrile following general procedure 2 gives the title compound as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09120804B2
Source datasetuspto-grants-2015_09
ORD IDord-f48b86b7aa694e3eb000eec0fe058af7
Source noteuspto-grants-2015_09