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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2273105Generated: October 31, 2026

Lithium Hydroxide → HCID 86731622, compound

https://huagongshe.com/reaction/2273105

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantHCID 86731618HCID 86731618—
ProductHCID 86731622HCID 86731622—

Reaction Steps

The title compound (D16) (60 mg) was prepared according to the general procedure for esters hydrolysis starting from (2R,4S)-3-(trifluoromethyl)benzyl 4-fluoro-1-(4-(trifluoromethyl)benzyl)pyrrolidine-2-carboxylate (D9) (110 mg). (LiOH: 2 eq; Reaction time: 18 hrs)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09120824B2
Source datasetuspto-grants-2015_09
ORD IDord-56a022307b49439f92dd42aecbef4072
Source noteuspto-grants-2015_09