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HRID2273106

反应详情

EQUATION

反应方程式

HRID 2273106 的结构方程式

REACTANTS

反应物

2
结构：[Li+].[OH-]
HCID3939

Lithium hydroxide anhydrous

HLiO

结构：COC(=O)[C@@]1(C)CCCN1Cc1cccc(C(F)(F)F)c1
HCID71204758

未命名化合物

PRODUCTS

生成物

1
结构：C[C@]1(C(=O)[O-])CCCN1Cc1cccc(C(F)(F)F)c1.[Li+]
HCID86731623

未命名化合物

PROCEDURE

实验过程

The title compound (D17) (37 mg) was prepared according to the general procedure for esters hydrolysis starting from (R)-methyl 2-methyl-1-(3-(trifluoromethyl)benzyl)pyrrolidine-2-carboxylate (D10) (47 mg). (LiOH: 2 eq; reaction time: 18 hrs).