HRID2273135

反应详情

EQUATION

反应方程式

REACTANTS

反应物

反应SMILES：COC(=O)c1ccc(C2(NC(=O)[C@H]3CCCCN3Cc3ccc(F)c(C(F)(F)F)c3)CC2)cc1

HCID71204754

未命名化合物

HCID178418351

未命名化合物

PRODUCTS

产物

反应SMILES：O=C([O-])c1ccc(C2(NC(=O)[C@H]3CCCCN3Cc3ccc(F)c(C(F)(F)F)c3)CC2)cc1.[Li+]

HCID71486667

未命名化合物

PROCEDURE

实验过程

The title compound (E13) (11.1 mg) was prepared according to the general procedure for esters hydrolysis starting from (R)-methyl 4-(1-(1-(4-fluoro-3-(trifluoromethyl)benzyl)piperidine-2-carboxamido)cyclopropyl)benzoate (D30) (35 mg). (LiOH H2O: 3 eq; reaction time: 3 hrs)