Cyclopropylamine → HCID 131733379, compound

HRID 2273152Notes

Reaction equation

HRID 2273152 reaction equation
Cl[SiH:2]1[N:6]([C:7]([CH3:10])([CH3:9])[CH3:8])[CH:5]=[CH:4][N:3]1[C:11]([CH3:14])([CH3:13])[CH3:12].[CH:15]1([NH2:18])[CH2:17][CH2:16]1>CCCCCC>[C:11]([N:3]1[CH:4]=[CH:5][N:6]([C:7]([CH3:10])([CH3:9])[CH3:8])[SiH:2]1[NH:18][CH:15]1[CH2:17][CH2:16]1)([CH3:14])([CH3:13])[CH3:12]

Participants

4

Reactant 2

HCID 69828CyclopropylamineHCID 713346111,3-Di-tert-butyl-2-chloro-2,3-dihydro-1H-1,3,2-diazasilole

Product 1

HCID 131733379HCID 131733379, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

In an argon atmosphere, 6.22 g (26.7 mmol) of Si(tBuNCHCHNtBu)(H)Cl was dissolved in 30 mL of hexane and after adding 3.14 g (56.0 mmol) of cyclopropylamine, the mixture was stirred at room temperature for 3 hours. Insoluble matters produced were separated by filtration, and the solvent was removed by distillation from the filtrate under atmospheric pressure. The obtained residue was distilled under reduced pressure (distillation temperature: 100° C./3.7×102 Pa) to obtain 1,3-di-tert-butyl-2-cyclopropylamino-1,3-diaza-2-silacyclopent-4-ene (Si(tBuNCHCHNtBu)(H)NHcPr) as a colorless liquid (yielded amount: 6.07 g, yield: 90%).

Workup

  1. customInsoluble matters produced
  2. customwere separated by filtration
  3. customthe solvent was removed by distillation from the filtrate under atmospheric pressure
  4. distillationThe obtained residue was distilled under reduced pressure (distillation temperature: 100° C./3.7×102 Pa)
  5. customto obtain

Sources & evidence

ORD record
ord-a690ccd62cbb4476baacbfaec4de0eef
Source dataset
uspto-grants-2015_09
Patent number
US09120825B2

Reaction notes

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