N-[2-[N-ethyl-N-[2-(2-fluoropyridin-3-yloxy)ethyl]amino]ethyl]-6-iodoimidazo[1,2-a]pyridine-2-carboxamide → N-[2-[N-ethyl-N-[2-(2-fluoropyridin-3-yloxy)ethyl]amino]ethyl]-6-iodoimidazo[1,2-a]pyridine-2-carboxamide dihydrochloride salt

Participants

Reaction Steps

This compound was prepared, starting from compound 76 (0.15 g, 0.30 mmol), according to the procedure developed for compound 11. Reaction time at room temperature: 12 h to give compound 77 (157 mg, 0.28 mmol) as a very hygroscopic beige solid. Yield 91%; mp 143-145° C.; IR (KBr) ν 1291, 1456, 1559, 1675, 2500-3600 cm−1; ESI-MS m/z 497.9 [M+H]+.

Provenance & Evidence