HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 90016643, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | L-Valine | HCID 6287 | — |
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Solvent | Isopropyl Acetate | HCID 7915 | — |
| Product | HCID 90016643 | HCID 90016643 | — |
Reaction Steps
L-Valine (117.2 g, 1.0 mol), KOH (85%, 66.0 g, 1 mol) and ethyl 3-oxobutanoate (140.2 mL, 1.1 mol) are dissolved in isopropyl acetate (1 L). The reaction mixture is heated to reflux using a Dean-Stark apparatus. 32 mL water are isolated during 1.75 h. A small quantity of precipitate is formed. 500 mL are distilled off.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09126896B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-d3b2d903e1974ea9baeb85ce4d7e4db7 |
| Source note | uspto-grants-2015_09 |