N-bromobutanimide → HCID 86666943, compound

HRID 2274119Notes

Reaction equation

HRID 2274119 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([C:9](=[O:11])[CH3:10])=[C:4]([OH:12])[CH:3]=1.[I:13]N1C(=O)CCC1=O.BrN1C(=O)CCC1=O>>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([C:9](=[O:11])[CH3:10])=[C:4]([OH:12])[C:3]=1[I:13]

Participants

4

Reactant 3

HCID 67184N-bromobutanimideHCID 120273N-IodosuccinimideHCID 138501674'',5''-DICHLORO-2''-HYDROXYACETOPHENONE

Product 1

HCID 86666943HCID 86666943, compoundYield 71%

Procedure

The desired compound was prepared according to the procedure of Example 6, Step 2, using 1-(4,5-dichloro-2-hydroxyphenyl)ethanone and N-iodosuccinimide (instead of N-bromosuccinimide) as the starting materials in 71% yield. LCMS for C8H6Cl2IO2 (M+H)+: m/z=330.9, 332.9. Found: 330.8, 332.9.

Sources & evidence

ORD record
ord-d55cd3a16d5e435bbc71460c8a9c92da
Source dataset
uspto-grants-2015_09
Patent number
US09126948B2

Reaction notes

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