HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2274150Generated: October 30, 2026
Morpholine → 7-(Morpholin-4-yl)quinazolin-4(3H)-one
https://huagongshe.com/reaction/2274150
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 7-Fluoroquinazolin-4(3H)-one | HCID 135398496 | — |
| Product | 7-(Morpholin-4-yl)quinazolin-4(3H)-one | HCID 135742360 | 50% |
Reaction Steps
20.0 g (0.122 mol) of 7-fluoro-3H-quinazolin-4-one were suspended in 80 ml of morpholine and stirred at an internal temperature of 90° C. for 16 h. Conventional work-up gave 14.1 g (Y=50%) of 7-morpholin-4-yl-3H-quinazolin-4-one (as described in Example 2.2, reaction step 1a).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09126952B2 |
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| Source dataset | uspto-grants-2015_09 |
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| ORD ID | ord-9f8e0088a4834da5b5addd2d6527216a |
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| Source note | uspto-grants-2015_09 |
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