反应详情

温度

80 °C

37.2 g (0.20 mol) of 6,7-difluoro-3H-quinazolin-4-one were suspended in 70 ml (0.80 mol) of morpholine and stirred at an internal temperature of 80° C. for 16 h. Conventional work-up gave 37.3 g (Y=74%) of 6-fluoro-7-morpholin-4-yl-3H-quinazolin-4-one.