2,4-Dichloropyrimidine → HCID 71631998, compound

HRID 2274241Notes

Reaction equation

HRID 2274241 reaction equation
[Cl:1][C:2]1[N:7]=[C:6](Cl)[CH:5]=[CH:4][N:3]=1.[NH:9]1[CH2:14][CH2:13][CH2:12][CH:11]([NH:15][C:16](=[O:22])[O:17][C:18]([CH3:21])([CH3:20])[CH3:19])[CH2:10]1>>[C:18]([O:17][C:16](=[O:22])[NH:15][CH:11]1[CH2:12][CH2:13][CH2:14][N:9]([C:6]2[CH:5]=[CH:4][N:3]=[C:2]([Cl:1])[N:7]=2)[CH2:10]1)([CH3:21])([CH3:19])[CH3:20]

Participants

3

Reactant 2

HCID 775312,4-DichloropyrimidineHCID 42330413-(Boc-amino)piperidine

Product 1

HCID 71631998HCID 71631998, compound

Procedure

tert-butyl(1-(2-chloropyrimidin-4-yl)piperidin-3-yl)carbamate was prepared using the procedure similar to COMPOUND 54 using 2,4-dichloropyrimidine and tert-butyl piperidin-3-ylcarbamate. MS (ES+) C14H21ClN4O2 requires: 312. Found: 313 [M+H]+

Sources & evidence

ORD record
ord-ffb1b08759954bf99440f1e1c309bc39
Source dataset
uspto-grants-2015_09
Patent number
US09126951B2

Reaction notes

Loading…