HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Bromomethyl)-1,2-difluorobenzene → (4-(3,4-Difluorobenzyl)morpholin-2-yl)methanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Bromomethyl)-1,2-difluorobenzene | HCID 581436 | — |
| Reactant | 1-[4-[(5-Chlorothien-2-yl)methyl]morpholin-2-yl]methanamine | HCID 21962888 | — |
| Product | (4-(3,4-Difluorobenzyl)morpholin-2-yl)methanamine | HCID 21962864 | — |
Reaction Steps
Intermediate 20 was prepared in an analogous manner to Intermediate 1 (Alternative Procedure) from Intermediate 19 and 3,4-difluorobenzyl bromide, followed by deprotection to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07560548B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-eeb9e02a9a3c4f57a7b54b4477e674cc |
| Source note | uspto-grants-2009_07 |