HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dioxane hydrochloride → 2-(3-(Naphthalen-1-ylmethyl)ureidooxy)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dioxane hydrochloride | HCID 20443148 | — |
| Reactant | HCID 86658801 | HCID 86658801 | — |
| Product | 2-(3-(Naphthalen-1-ylmethyl)ureidooxy)acetic acid | HCID 53397538 | 100% |
Reaction Steps
According to the procedure described in the synthesis method of Compound VI-9, tert-butyl 2-(3-(naphthalen-1-ylmethyl)ureidooxy)acetate (Compound V-7) (50 mg, 0.15 mmol) was reacted with 4N HCl/dioxane (2 ml) to obtain the title compound (41 mg, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09126981B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-d58831a1cb5f4f45b2b66f728d152a17 |
| Source note | uspto-grants-2015_09 |