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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2274631Generated: November 1, 2026

1,4-Dioxane hydrochloride → 2-(3-Ethylureidooxy)acetic acid

https://huagongshe.com/reaction/2274631

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Dioxane hydrochlorideHCID 20443148—
ReactantHCID 86658798HCID 86658798—
Product2-(3-Ethylureidooxy)acetic acidHCID 53397416100%

Reaction Steps

According to the procedure described in the synthesis method of Compound VI-9, tert-butyl 2-(3-ethylureidooxy)acetate (Compound V-8) (33 mg, 0.15 mmol) was reacted with 4N HCl/dioxane (2 ml) to obtain the title compound (24 mg, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09126981B2
Source datasetuspto-grants-2015_09
ORD IDord-168772e7c6f24df69f9b6bfbb0d706fe
Source noteuspto-grants-2015_09