2,2-Diethoxyethylamine → HCID 67304207, compound

HRID 2274639Notes

Reaction equation

HRID 2274639 reaction equation
[CH2:1]([O:3][CH:4]([O:7][CH2:8][CH3:9])[CH2:5][NH2:6])[CH3:2].[N:10]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[C:13]([CH:20]=O)=[CH:12][CH:11]=1>>[CH2:1]([O:3][CH:4]([O:7][CH2:8][CH3:9])[CH2:5][NH:6][CH2:20][C:13]1[C:14]2[C:19](=[CH:18][CH:17]=[CH:16][CH:15]=2)[N:10]=[CH:11][CH:12]=1)[CH3:2]

Participants

3

Reactant 2

HCID 695242,2-DiethoxyethylamineHCID 780724-Quinolinecarboxaldehyde

Product 1

HCID 67304207HCID 67304207, compoundYield 109.3%

Procedure

According to the procedure described in the synthesis method of Compound IX-2 with the modification that the reaction was carried out overnight, 2,2-diethoxyethanamine (3.64 ml, 25 mmol) was reacted with 4-quinolinecarboxaldehyde (3.14 g, 20 mmol) to obtain the title compound (6.0 g, 88%).

Workup

  1. customdescribed in the synthesis method of Compound IX-2 with the modification that the reaction

Sources & evidence

ORD record
ord-9fea1c88afea4c89af188799718df710
Source dataset
uspto-grants-2015_09
Patent number
US09126981B2

Reaction notes

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