反应详情

1 (0.33 g, 1.5 mmol), TEA (0.209 mL, 1.5 mmol) and octylbromide (0.258 mL, 1.5 mmol) were dissolved in 10 mL of EtOH and kept under reflux overnight. The solvent was removed and the remaining oil was purified by flash-chromatography on silica gel, applying a CHCl3/MeOH gradient.

1. temperatureunder reflux overnight
2. customThe solvent was removed
3. customthe remaining oil was purified by flash-chromatography on silica gel