HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 68442079, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 68444847 | HCID 68444847 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 68442079 | HCID 68442079 | — |
Reaction Steps
Through a solution of ethyl 5-bromo-3-{[4-(tert-butoxycarbonyl)-piperazin-1-yl]sulfonyl}-1-(phenylsulfonyl)-1H-indole-2-carboxylate (44 mg, 0.067 mmol) in 5 mL of ethyl acetate at 0° C. was bubbled HCl gas for 2 minutes. After stirring an additional 30 minutes, the reaction was concentrated in vacuo to provide the titled product as a white solid. ESI+MS: 556.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07560546B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-d635bf2d63ec44ae99778e976ce4e379 |
| Source note | uspto-grants-2009_07 |