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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 227476Generated: October 30, 2026

Hydrochloric Acid → HCID 68442079, compound

https://huagongshe.com/reaction/227476

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 68444847HCID 68444847—
SolventEthyl AcetateHCID 8857—
ProductHCID 68442079HCID 68442079—

Reaction Steps

Through a solution of ethyl 5-bromo-3-{[4-(tert-butoxycarbonyl)-piperazin-1-yl]sulfonyl}-1-(phenylsulfonyl)-1H-indole-2-carboxylate (44 mg, 0.067 mmol) in 5 mL of ethyl acetate at 0° C. was bubbled HCl gas for 2 minutes. After stirring an additional 30 minutes, the reaction was concentrated in vacuo to provide the titled product as a white solid. ESI+MS: 556.0 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07560546B2
Source datasetuspto-grants-2009_07
ORD IDord-d635bf2d63ec44ae99778e976ce4e379
Source noteuspto-grants-2009_07