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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 227477Generated: October 29, 2026

4-Methoxybenzenesulfonyl chloride → HCID 68442814, compound

https://huagongshe.com/reaction/227477

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxybenzenesulfonyl chlorideHCID 7401—
ReactantTriethylamineHCID 8471—
ReactantHCID 68442079HCID 68442079—
SolventDichloromethaneHCID 6344—
ProductHCID 68442814HCID 68442814—

Reaction Steps

To a solution ethyl 5-bromo-1-(phenylsulfonyl)-3-(piperazin-1-ylsulfonyl)-1H-indole-2-carboxylate hydrochloride (20 mg, 0.034 mmol) in 1.0 mL of dichloromethane at room temperature was added triethylamine (0.019 mL, 0.14 mmol), followed by 4-(methoxy)benzenesulfonyl chloride (8.0 mg, 0,041 mmol). After stirring overnight, the solvent was removed under a stream of nitrogen to provide the titled compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07560546B2
Source datasetuspto-grants-2009_07
ORD IDord-9cf55de87a694faeb7007d0c55d14351
Source noteuspto-grants-2009_07