HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(Trifluoromethyl)indole → 3-iodo-6-(trifluoromethyl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(Trifluoromethyl)indole | HCID 2777523 | — |
| Reactant | 6-fluoro-3-iodo-1-(phenylsulfonyl)-1H-indole | HCID 67279837 | — |
| Product | 3-iodo-6-(trifluoromethyl)-1H-indole | HCID 118060679 | 98% |
Reaction Steps
Following the general method as outlined in Intermediate 3, starting from 6-(trifluoromethyl)-1H-indole (0.97 g; 5.24 mmol), 1.60 g (98%) of the title compound was obtained as a red solid, which was used directly without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09126984B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-4f51ff963c2a4360820e13464be79b78 |
| Source note | uspto-grants-2015_09 |