HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,6-difluoro-3-iodo-1-(phenylsulfonyl)-1H-indole → 3-iodo-1-(phenylsulfonyl)-6-(trifluoromethyl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,6-difluoro-3-iodo-1-(phenylsulfonyl)-1H-indole | HCID 118060283 | — |
| Reactant | 3-iodo-6-(trifluoromethyl)-1H-indole | HCID 118060679 | — |
| Product | 3-iodo-1-(phenylsulfonyl)-6-(trifluoromethyl)-1H-indole | HCID 118060607 | 45% |
Reaction Steps
Following the general method as outlined in Intermediate 28, starting from 3-iodo-6-(trifluoromethyl)-1H-indole (Intermediate 39; 1.60 g; 5.14 mmol), 1.06 g (45%) of the title compound was obtained as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09126984B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-50b14541b5194c119e1a5499af2d589e |
| Source note | uspto-grants-2015_09 |