1-(2-Hydroxyethyl)-2-pyrrolidinone → 2-(2-Oxopyrrolidin-1-yl)ethyl methanesulfonate

HRID 2274788노트

반응식

HRID 2274788 반응식
[CH3:1][S:2]([O:5][CH2:6][CH2:7][N:8]1[CH2:12][CH2:11]N[C:9]1=[O:13])(=[O:4])=[O:3].O[CH2:15]CN1CCCC1=O>>[CH3:1][S:2]([O:5][CH2:6][CH2:7][N:8]1[CH2:12][CH2:11][CH2:15][C:9]1=[O:13])(=[O:4])=[O:3]

참가 물질

3

반응물 2

HCID 769801-(2-Hydroxyethyl)-2-pyrrolidinoneHCID 190455732-(2-Oxoimidazolidin-1-yl)ethyl methanesulfonate

생성물 1

HCID 446271162-(2-Oxopyrrolidin-1-yl)ethyl methanesulfonate수율 50%

실험 절차

Following the general method as outlined in Intermediate 31, starting from 1-(2-hydroxyethyl)pyrrolidin-2-one (500 mg; 3.87 mmol), 400 mg (50%) of the title compound as a yellow oil, which was used directly without further purification.

출처 및 근거

ORD 기록
ord-b75c381d1e1f4dc482de44e83bf7e44e
출처 데이터셋
uspto-grants-2015_09
특허 번호
US09126984B2

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