HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Hydroxyethyl)-2-pyrrolidinone → 2-(2-Oxopyrrolidin-1-yl)ethyl methanesulfonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Hydroxyethyl)-2-pyrrolidinone | HCID 76980 | — |
| Reactant | 2-(2-Oxoimidazolidin-1-yl)ethyl methanesulfonate | HCID 19045573 | — |
| Product | 2-(2-Oxopyrrolidin-1-yl)ethyl methanesulfonate | HCID 44627116 | 50% |
Reaction Steps
Following the general method as outlined in Intermediate 31, starting from 1-(2-hydroxyethyl)pyrrolidin-2-one (500 mg; 3.87 mmol), 400 mg (50%) of the title compound as a yellow oil, which was used directly without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09126984B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-b75c381d1e1f4dc482de44e83bf7e44e |
| Source note | uspto-grants-2015_09 |