HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18471417, compound → HCID 118060369, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18471417 | HCID 18471417 | — |
| Reactant | 6-fluoro-1-(phenylsulfonyl)-3-(1H-pyrazol-4-yl)-1H-indole | HCID 118060134 | — |
| Product | HCID 118060369 | HCID 118060369 | 59% |
Reaction Steps
Following the general method as outlined in Intermediate 16, starting from 6-fluoro-1-(phenylsulfonyl)-3-(1H-pyrazol-4-yl)-1H-indole (Intermediate 5; 600 mg; 1.76 mmol) and 1,4-dioxaspiro[4.5]decan-8-ylmethanesulfonate (498 mg; 2.11 mmol), 500 mg (59%) of the title compound was obtained as a white solid after purification by reverse phase flash chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09126984B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-30a8a4f293874bf38c9ac920f8fbdd84 |
| Source note | uspto-grants-2015_09 |