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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 227481Generated: October 29, 2026

Morpholine → HCID 10459581, compound

https://huagongshe.com/reaction/227481

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactantethyl 5-chloro-3-(chlorosulfonyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylateHCID 22401482—
ReactantHCID 57445036HCID 57445036—
Reactantethyl 3-(chlorosulfonyl)-5-bromo-1-(phenylsulfonyl)-1H-indole-2-carboxylateHCID 86592455—
ProductHCID 10459581HCID 10459581—

Reaction Steps

Following the procedures described in Steps D and E of Example 1, replacing in Step D ethyl 5-chloro-3-(chlorosulfonyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylate with ethyl 5-bromo-3-(chlorosulfonyl)-1-(phenylsulfonyl)-1H-indole-2carboxylate, and morpholine with 1-(3-morpholin-4-ylpropyl)piperazin-2-one hydrochloride, the title compound was obtained. ESI+MS: 528.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07560546B2
Source datasetuspto-grants-2009_07
ORD IDord-550823dd0ea944929fdbd440cf97e679
Source noteuspto-grants-2009_07