HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 88861843, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 68182913 | HCID 68182913 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 88861843 | HCID 88861843 | — |
Reaction Steps
To a solution containing 130 mg (0.33 mmol) of (S)-tert-butyl 2-(4-(4-fluorophenyl)-1-oxo-2,8-diazaspiro[4.5]decan-8-yl)ethylcarbamate and 5 mL of DCM was added 1 mL of TFA. The reaction mixture was allowed to stir at room temperature overnight. The solvents were removed under reduced pressure and the residue was used without further purification: LCMS m/z: 292.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09127005B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-f29b0289816a44208ead5c6f4aea5c7a |
| Source note | uspto-grants-2015_09 |