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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2274985Generated: October 31, 2026

Trifluoroacetic acid → HCID 88861843, compound

https://huagongshe.com/reaction/2274985

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 68182913HCID 68182913—
SolventDichloromethaneHCID 6344—
ProductHCID 88861843HCID 88861843—

Reaction Steps

To a solution containing 130 mg (0.33 mmol) of (S)-tert-butyl 2-(4-(4-fluorophenyl)-1-oxo-2,8-diazaspiro[4.5]decan-8-yl)ethylcarbamate and 5 mL of DCM was added 1 mL of TFA. The reaction mixture was allowed to stir at room temperature overnight. The solvents were removed under reduced pressure and the residue was used without further purification: LCMS m/z: 292.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09127005B2
Source datasetuspto-grants-2015_09
ORD IDord-f29b0289816a44208ead5c6f4aea5c7a
Source noteuspto-grants-2015_09