Isobutanol → HCID 66960470, compound

HRID 2275726Notes

Reaction equation

HRID 2275726 reaction equation
[CH3:1][C:2]1([CH3:19])[C:6]([CH3:8])([CH3:7])[O:5][B:4]([C:9]2[CH:14]=[CH:13][C:12](CC(O)=O)=[CH:11][CH:10]=2)[O:3]1.[CH3:20][CH:21]([CH3:24])[CH2:22][OH:23]>C(O)C>[CH3:7][C:6]1([CH3:8])[C:2]([CH3:19])([CH3:1])[O:3][B:4]([C:9]2[CH:10]=[CH:11][C:12]([CH2:7][CH2:6][C:2]([O:23][CH2:22][CH:21]([CH3:24])[CH3:20])=[O:3])=[CH:13][CH:14]=2)[O:5]1

Participants

4

Reactant 2

HCID 6560IsobutanolHCID 37190022-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetic Acid

Product 1

HCID 66960470HCID 66960470, compoundYield 67%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Isobutyl 3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate (67%) was prepared according to Example 192, Step A described above, substituting 3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoic acid for 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetic acid and 2-methylpropan-1-ol for ethanol.

Sources & evidence

ORD record
ord-4edf8f0df3de411b95461174eec88d1f
Source dataset
uspto-grants-2015_09
Patent number
US09126940B2

Reaction notes

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