Methanol → HCID 49852656, compound

HRID 2275987Notes

Reaction equation

HRID 2275987 reaction equation
C(Cl)Cl.[CH3:4][S:5][C:6]1[CH:16]=[C:15]2[C:10](=[C:11]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[C:12]([O:14]2)=[O:13])[CH:9]=[CH:8][CH:7]=1.C[OH:24]>>[CH3:4][S:5][C:6]1[CH:16]=[C:15]2[C:10](=[C:11]([C:17]3[CH:22]=[CH:21][C:20]([OH:24])=[CH:19][CH:18]=3)[C:12]([O:14]2)=[O:13])[CH:9]=[CH:8][CH:7]=1

Participants

4

Reactant 3

HCID 887Methanol2×HCID 6344Dichloromethane2×HCID 49852657HCID 49852657, compound

Product 1

HCID 49852656HCID 49852656, compound

Procedure

TLC(CH2Cl2:MeOH, 92:8 v/v): Rf=0.55; UV/vis λmax 262 nm, 432 nm; HRMS (m/z): [M]+ calculated for C16H12O3S, 285.0585. found 285.0578. See Table 2 for NMR data. Roseobacticide B. TLC(CH2Cl2:MeOH, 92:8 v/v): Rf=0.58; UV/vis λmax 262 nm, 316 nm, 430 nm; HRMS (m/z): [M]+calculated for C16H12O2S, 269.0637. found 269.0635. See Table 3 for NMR data.

Sources & evidence

ORD record
ord-2d0648749ab64e85b1257753d797e1b7
Source dataset
uspto-grants-2015_09
Patent number
US09131687B2

Reaction notes

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