Aniline → HCID 11514527, compound

HRID 227629Notes

Reaction equation

HRID 227629 reaction equation
[C:1]([C:3]([C:17]#[N:18])=[C:4]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[CH2:5][CH2:6][CH2:7][C:8]([OH:10])=O)#[N:2].Cl.[CH3:20][NH:21][CH3:22].NC1C=CC=CC=1>>[C:17]([C:3]([C:1]#[N:2])=[C:4]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[CH2:5][CH2:6][CH2:7][C:8]([N:21]([CH3:22])[CH3:20])=[O:10])#[N:18]

Participants

4

Reactant 3

HCID 6115AnilineHCID 10473Dimethylamine, hydrochlorideHCID 11665887HCID 11665887, compound

Product 1

HCID 11514527HCID 11514527, compound

Procedure

The desired product was prepared by substituting 6,6-dicyano-5-phenyl-5-hexenoic acid (prepared by substituting 5-oxo-5-phenylpentanoic acid for Example 1A in Example 1B) and dimethylamine hydrochloride for Example 66B and aniline, respectively, in Example 66C. MS (ESI(−)) m/e 266 (M−H)−.

Sources & evidence

ORD record
ord-ce066f14e24949f2a68e5f2412ca45e4
Source dataset
uspto-grants-2009_07
Patent number
US07560552B2

Reaction notes

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