Hydrochloric Acid → HCID 49819587, compound

Participants

Reaction Steps

2-[3-(2-tert-butoxycarbonylaminoacetylamino)-4-methoxybenzylsulfanyl]-8-ethyl-9-methyl-6-morpholino-9H-purine (Compound 62) (140 mg, 0.24 mmol) was dissolved in tetrahydrofuran (15 ml), 4N-hydrogen chloride in dioxane (2 ml) and stirred for 8 hours. After distilling away the solvent under reduced pressure, the residue was washed with ether to obtain 103 mg (83% yield) of Compound 28.

Provenance & Evidence