Potassium Carbonate → HCID 86725184, compound

Participants

Reaction Conditions

Reaction Steps

To the solution of acid 15 (0.5 mmol) in DMF (5 mL) was added chloromethyl isopropyl carbonate (1 mmol), followed by K2CO3 (0.75 mmol). The resulting mixture was stirred at 50° C. for 18 hours and brought to room temperature and concentrated. The residue was purified by purified by prep-HPLC (C18, acetonitrile and water as mobile phases, 0.1% formic acid) to obtain the titled compound.

Provenance & Evidence