HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl cyanoacetate → HCID 70982357, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl cyanoacetate | HCID 7747 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | N-Hydroxy-2-(trifluoromethyl)benzene-1-carboximidoyl chloride | HCID 53395456 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 70982357 | HCID 70982357 | 85.1% |
Reaction Steps
In a similar manner as described in Preparation Example 17, by using methanol (160 mL), N-hydroxy-2-(trifluoromethyl)benzimidoyl chloride (8.00 g, 33.39 mmol), methylcyanoacetate (4.14 g, 41.74 mmol) and sodium methoxide (3.61 g, 66.78 mmol), a white solid required compound (8.13 g, 28.42 mmol, 85%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09132126B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-7f61e1c883a9422d86daea1909661a32 |
| Source note | uspto-grants-2015_09 |