反应详情

In a similar manner as described in Preparation Example 25, by using methanol (60 mL), methyl-5-amino-3-(2-fluorophenyl)isoxazol-4-carboxylate (6.0 g, 25.40 mmol) and 3% sodium hydroxide aqueous solution (60 mL), a white solid required compound (3.18 g, 14.33 mmol, 56%) was obtained.

1. customIn a similar manner as described in Preparation Example 25