反应详情

In a similar manner as described in Preparation Example 25, by using methanol (60 mL), methyl-5-amino-3-(4-(trifluoromethoxy)phenyl)isoxazol-4-carboxylate (6.0 g, 19.85 mmol) and 3% sodium hydroxide aqueous solution (60 mL), a white solid required compound (4.32 g, 15.02 mmol, 76%) was obtained.

1. customIn a similar manner as described in Preparation Example 25