Ethanol → HCID 86709611, compound

Participants

Reaction Conditions

Reaction Steps

(4-(3,4-dichlorophenyl)piperazine-1-yl)(5-methyl-3-(2-(trifluoromethoxy)phenyl)isoxazol-4-yl)methanone (100 mg, 0.20 mmol) was dissolved in acetone (10 mL), cooled to 0° C. and slowly added with hydrochloric ethanol (10%, 73 mg, 0.20 mmol). The resultant product was stirred at room temperature for 8 hours, filtered, and dried so as to provide a white solid required compound (84 mg, 1.20 mmol, 78%).

Provenance & Evidence