1-Methylpiperazine → HCID 57756881, compound

Participants

Reaction Steps

The process is performed in a manner similar to that described in Example 39 but starting with N-methylpiperazine and ethyl 5-carbamoyl-4-{4-[3-(2-fluoro-5-trifluoromethylphenyl)ureido]phenyl}-1H-pyrrole-3-carboxylate. After a similar work-up, 3-{4-[3-(2-fluoro-5-trifluoromethylphenyl)ureido]phenyl}-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrole-2-carboxamide is obtained; ES+: m/z=533 [M+H]+.

Provenance & Evidence